Paternity inclusion in the presence of multiple exclusions.
نویسندگان
چکیده
The resolution of a paternity case is presented in which two indirect exclusions were found for the alleged father during routine paternity testing. Genetic studies on family members of the alleged father elucidated the inheritance pattern within the phosphoglucomutase (PGM1) and Duffy (Fy) blood group systems.
منابع مشابه
Are Two Exclusions Enough to Exclude in Paternity Testing? Analysis of 17 Str, D1s80 and Hla-a, B, Drb, and Dqb1 in Two Cases with Only Two Exclusions
It is widely accepted that two or more STR exclusions are enough to exclude in a paternity testing dispute. Routinely we analyze 12 Short Tandem repeat loci (STR) in our paternity testing program. When only one or two exclusions are found, we increase the number of STR analyzed to 17 plus D1S80 in order to find additional exclusions (Power of exclusion 99.9999%). Occasionally, the highly discri...
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In parentage testing when one parent is excluded, the distribution of the number of loci showing exclusion due to mutations of the transmitting alleles is derived, and it is contrasted with the expected distribution when the exclusion is caused by nonpaternity. This theory is applied to allele frequency data on short tandem repeat loci scored by PCR analysis, and VNTR data scored by Southern bl...
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ورودعنوان ژورنال:
- Annals of clinical and laboratory science
دوره 21 4 شماره
صفحات -
تاریخ انتشار 1991